Generally if you tune for your highest head speed the others will fly pretty well... unless you're doing extreme hs differences like 1400 IU1 to 2200 IU2. The main rotor has more of a physical gyroscopic effect at higher head speeds which can also make cyclic rates feel a little slower and the system as a whole may generate slightly higher vibrations than at lower head speeds. There are many factors that may contribute to different gain settings as well as rate settings. Add in build technique and your personal "feel" preferences, governor performance, blade weight & balance, etc etc etc and you have a big part of why everyone's helicopter will have a unique tune.